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| VGX
Collaborators Present at the ICAAC
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| Blue
Bell, PA – September 27, 2006 – |
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VGX Pharmaceuticals announced that the Company’s
collaborators from the Adult AIDS Clinical Trials Group (AACTG) have presented
a scientific poster at the 46th Annual International Conference on Antimicrobial
Agents and Chemotherapy (ICAAC) in San Francisco. The poster presentation
entitled, “A5200, Phase I/II Trial of the Anti-HIV Activity of Mifepristone
(MIF) in HIV Infected Subjects (ICAAC06-A-1171-ASM) presented results
from the A5200 study conducted by AACTG and VGX as the first Phase I/II
clinical trials of PICTOVIR™, a lead drug compound for the treatment
of HIV infection (See Press Released dated 12/29/2005).
A5200 Study’s Chairman Professor Michael Para, MD of Ohio State
University presented poster on behalf of the A5200 team. This double-blinded,
placebo-controlled, multi-center, multi-dose, randomized, Phase I/II study
was conducted at 8 different AACTG site, including Ohio State University,
UCLA, University of Pennsylvania, University of Washington, and Georgetown
University. PICTOVIR™ doses of 75 to 225 mg/d were safe and well-tolerated
and in vivo biologic activity was confirmed in the higher dosage arms.
Based upon these results, the VGX Pharmaceuticals is currently conducting
additional Phase II clinical trials for PICTOVIR™ with higher dosage
levels to determine the dosage level necessary to achieve a clinically
significant antiviral effect.
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Web site contain information that includes or is based upon forward-looking
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They use words such as "anticipate," "estimate,"
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include statements relating to future actions, prospective products
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forward-looking statements here or in other publications may turn
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by known or unknown risks and uncertainties. Many such factors will
be important in determining our actual future results. Consequently,
no forward-looking statement can be guaranteed, and forward-looking
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market conditions, competitive product development, product availability,
current and future branded and generic competition, federal and state
regulations and legislation, manufacturing issues, timing of the elimination
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Our actual results may vary materially, and there are no guarantees
about the performance or valuation of VGX stock. It is also important
to read the disclosure notice contained in many of the individual
VGX documents available on this Web site as many contain important
information on such cautionary factors as of the date of the individual
document. We undertake no obligation to correct or update any forward-looking
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we make on related subjects in our reports. |
About
VGX Pharmaceuticals
VGX Pharmaceuticals is a leading biopharmaceutical company with strong product
candidates for the treatment of infectious diseases including HIV and hepatitis
C virus (HCV) as well as cancer and inflammatory diseases. The Company’s
clinical development programs include PICTOVIR™ for HIV infection
and VGX-410C for chronic HCV infection, which are currently in Phase II
clinical trials. In addition, a Phase I clinical trial will be initiated
in 2007 for the Company’s lead cancer drug compound, VGX-150 for the
treatment of Melanoma. Moreover, VGX Pharmaceuticals’ therapeutic
platform is designed to advance a strong and continual pipeline of additional
drug candidates into the clinic with VGX-100 for cancer therapy and VGX-1027
and VGX-750 for inflammatory diseases currently in development. The product
candidates and technology programs are protected by the Company’s
extensive global intellectual property portfolio. More information about
VGX can be found at www.vgxp.com.
Company Contact:
Kevin W. Rassas
Senior Vice President
Tel. 267.440.4208
Fax 267.440.4242
E-mail: Rassas@vgxp.com
www.vgxp.com
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